Thursday, October 15th
Hall A Hall B
08:45-09:00 Welcome Coffee
09:00-12:00 IACH 1: Workshop
12:00-12:30 Lunch Break
12:30-13:00 IACH 2: Awards Session
13:00-14:15 Transplant 1: Advances in Allogeneic Transplantation 13:00-14:15 COMydAL 1: MDS I
Moderators: Arnon Nagler, Israel; TBA Moderators: Matteo Della Porta, Italy; Amy DeZern, USA
13:00-13:15 Conditioning regimen:
Maud D’Aveni, France
13:00-13:15 A new MDS classification ahead?
Robert Hasserjian, USA
13:15-13:30 Revisited TCI:
Alexandros Spyridonidis, Greece
13:15-13:30 AI in diagnosis and prognostication of MDS and CMML:
Matteo Della Porta, Italy
13:30-13:45 Graft manipulation and Tregs:
TBA
13:30-13:45 Is there a border between AA and hMDS?
Amy DeZern, USA
13:45-14:00 Novel combination for GVHD prophylaxis:
Annalisa Ruggeri, Italy
13:45-14:00 Germline predisposition in MDS, diagnosis and impact on therapy:
Marie Sebert, France
14:00-14:15 Panel discussion: All session faculty 14:00-14:15 Panel discussion: All session faculty
14:15-15:30 Transplant 2: HCT/CT in Malignancies 14:15-15:30 COMydAL 2: MDS II
Moderators: Eolia Brissot, France; TBA Moderators: Lionel Adès, France; Valeria Santini, Italy
14:15-14:30 Should we transplant TP53 mutated AML?
Xavier Poiré, Belgium
14:15-14:30 Transplant for MDS in 2026?
David Valcárcel, Spain
14:30-14:45 CAR-T cells or alloHCT for very high-risk B-ALL in first line:
He Huang, China
14:30-14:45 Diagnosis and treatment of VEXAS and MDS:
Jérome Hadjadj, France
14:45-15:00 T-ALL:
TBA
14:45-15:00 Therapy of HR MDS: are target drugs the onlyl hope?
Lionel Adès, France
15:00-15:15 State-of-the-art CD19 CAR-T cell therapy in DLBCL and future directions:
TBA
15:00-15:15 Navigating the treatment of LR-MDS:
TBA
15:15-15:30 Panel discussion: All session faculty 15:15-15:30 Panel discussion: All session faculty
15:30-16:45 Industry Symposium 15:30-16:45 Industry Symposium
16:45-17:00 Coffee Break
17:00-18:15 Transplant 3: HCT/CT in Non-Malignant Disease  17:00-18:15 COMydAL 3: CMML, MDS/MPN and others
Moderators: TBA Moderators: Francesco Onida, Italy; Valeria Santini, Italy
17:00-17:15 AlloHCT for sickle cell disease?
TBA
17:00-17:15 New directions in management of TP53 mutated myeloid neoplasms: Maximilian Stahl, USA
17:15-17:30 Gene therapy for sickle cell disease?
TBA
17:15-17:30 Evolving use of oral HMAs in myeloid malignancies:
Daniel Wiseman, UK
17:30-17:45 CAR-T cells in autoimmune disease:
Dimitrios Mougiakakos, Germany
17:30-17:45 Recommendation transplantation in CMML and MDS/MPN:
Francesco Onida, Italy
17:45-18:00 Gene transfer vs gene editing: efficacy and safety issue:
TBA
17:45-18:00 Biology and treatment of CMML:
Mrinal Patnaik, USA
18:00-18:15 Panel discussion: All session faculty 18:00-18:15 Panel discussion: All session faculty

IACH track

COMydAL track

COLYM track

MPNCo&D track

Transplant track

Friday, October 16th
Hall A Hall B
08:30-09:45 Transplant 4: Complications 08:30-09:45 COMydAL 4: AML I
Moderators: Bipin Savani, USA;TBA Moderators: Tamara Vasilj, Croatia; Amer Zeidan, USA
08:30-08:45 Endothelial dysfunction: TMA?
TBA
08:30-08:45 MyeloMatch and pivotal AML studies to watch for in the next 3 years:
Selina Luger, USA
08:45-09:00 Nutrition and frailty scale:
María Queralt Salas, Spain
08:45-09:00 An update on FLT3 inhibitors use in AML:
TBA
09:00-09:15 Antibiotic stewardship in alloHCT:
TBA
09:00-09:15 An update on IDH inhibitors use in AML:
Stéphane De Botton, France
09:15-09:30 CNS complications in HCT and CAR-T?
Zinaida Perić, Croatia
09:15-09:30 An update on menin inhibitors use in AML:
Amer Zeidan, USA
09:30-09:45 Panel discussion: All session faculty 09:30-09:45 Panel discussion: All session faculty
09:45-10:00 Coffee Break
10:00-11:15 Transplant 5: Post HCT Management 10:00-11:15 COMydAL 5: AML II
Moderators: Anne Huynh, France; TBA Moderators: Sanam Loghavi, USA; Amer Zeidan, USA
10:00-10:15 Management of MRD in pre and post alloHCT strategies in AML:
Jaime Sanz Caballer, Spain
10:00-10:15 How should TP53 mutated myeloid neoplasms be classified?
Coleman Lindsley, USA
10:15-10:30 Maintenance in AML:
Eolia Brissot, France
10:15-10:30 Updates on clinical use of MRD for clinical management of AML: Christoph Röllig, Germany
10:30-10:45 DLI:
Raynier Devillier, France
10:30-10:45 Learnings from HARMONY about genetics determinants of outcomes in AML:
Lars Bullinger, Germany
10:45-11:00 Post HCT rehabilitation:
Didier Blaise, France
10:45-11:00 Harmonization efforts of classifications for AML and MDS: Sanam Loghavi, USA
11:00-11:15 Panel disucssion: All session faculty 11:00-11:15 Panel disucssion: All session faculty
11:15-12:30 Industry Symposium 11:15-12:30 Industry Symposium
12:30-13:00 Lunch Break
13:00-14:15 COLYM 1: From Biology to Bedside: What Will Really Change Practice? 13:00-13:05 Opening: Claire Harrison, UK; Ruben Mesa, USA; Naveen Pemmaraju, USA
13:05-14:15 MPNCo&D 1: Redefining disease and risk: are we stratifying patients correctly?
Moderators: TBA Moderators: Florian Heidel, Germany; Francesca Palandri, Italy
13:00-13:05 Case report:
TBA
13:05-13:20 Patient perspective on MPN priorities for 2026 and beyond: Werner Zinkland, Germany
13:05-13:15 Discussion 13:20-13:35 Molecular risk models vs clinical judgement: are mutations driving overtreatment? Should we use them more in ET and PV:
Jean-Jacques Kiladjian, France
13:15-13:30 Molecular subtyping and functional genomics: what is ready for routine care?
Miguel Angel Piris, Spain
13:35-13:50 Clonal hematopoiesis vs early MPN: when does ‘watch and wait’ become unsafe?
Adam Mead, UK
13:30-13:45 ctDNA as a decision-making tool: hype, hope, or hard evidence?
Sven Borchmann, Germany
13:50-14:05 Symptoms, spleen, survival: which outcome should drive first-line therapy choices in MF?
Claire Harrison, UK
13:45-14:00 Emerging biomarkers for response prediction to novel agents:
Brian Hill, USA
14:05-14:15 Panel discussion: All session faculty
14:00-14:15 Panel discussion: All session faculty
14:15-15:30 Industry Symposium 14:15-15:30 Industry Symposium
15:30-16:45 COLYM 2: Redefining Frontline Therapy: Risk, Response, and Reality 15:30-16:45 MPNCo&D 2: Anemia in myelofibrosis: mechanism-driven therapy or trial-and-error?
Moderators: TBA Moderators: Adam Mead, UK; David Ross, Australia
15:30-15:35 Case report:
TBA
15:30-15:45 What causes anemia in MF — cytokines, hepcidin, marrow failure, or treatment effect?
David Ross, Australia
15:35-15:45 Discussion 15:45-16:00 ESAs, danazol, steroids: obsolete, underused, or still foundational? Susanne Isfort, Germany
15:45-16:00 Biology-driven frontline strategies in aggressive B-cell lymphomas: Andrew Davies, UK 16:00-16:15 Novel agents targeting anemia pathways in MF: Searching for the Holy Grail:
Ruben Mesa, USA
16:00-16:15 Frontline therapy in high-risk subgroups: elderly fit patients with LBCL:
Farrukh Awan, USA
16:15-16:35 Anemia as a prognostic marker vs a treatment-limiting toxicity: should it dictate therapy choice?
Yes: Juan Carlos Hernandes-Boluda, Spain
No: Francesca Palandri, Italy
16:15-16:30 Managing primary refractory and early relapsed aggressive B-cell lymphomas: optimizing salvage and bridging strategies:
Rémy Duléry, USA
16:35-16:45 Panel discussion: All session faculty
16:30-16:45 Panel discussion: All session faculty
16:45-17:00 Coffee Break
17:00-18:15 IACH 3
Saturday, October 17th
Hall A Hall B
08:30-09:45 COLYM 3: Sequencing in Relapsed Lymphoma: Making Sense of Too Many Options 08:30-09:45 MPNCo&D 3: Next-generation targeted therapies: beyond JAK inhibition in MF
Moderators: Mohamed Kharfan-Dabaja, USA; TBA Moderators: Susanne Isfort, Germany; Andreas Reiter, Germany
08:30-08:35 Case report: TBA 08:30-08:45 Selective pathway targeting (e.g. hepcidin, ACVR1, BCL-2 family, Xpo1, MDM2): real differentiation or incremental gains?
Jennifer O’Sullivan, UK
08:35-08:45 Discussion
08:45-09:00 Bispecific antibodies vs cellular therapies in FL: how to choose in real-life practice:
Julio Chavez, USA
08:45-09:00 Early signals from novel agents targeting CALR in MF: how should clinicians interpret phase 1-2 data?
Bethan Psaila, UK
09:00-09:15 Treatment sequencing in relapsed / refractory MZL: what do we do next?
Côme Bommier, France
09:00-09:15 Early data on novel JAK inhibitors: molecular markers, phenotype, or treatment history?
John Mascarenhas, USA
09:15-09:30 Treatment sequencing in relapsed / refractory MCL: what do we do next?
Carlo Visco, Italy
09:15-09:35 Combination strategies for upfront management: all patients INT-1 or above with splenomegaly and symptoms should receive combination therapy if trials are positive
Yes: Francesco Passamonti, Italy
No: Florian Heidel, Germany
09:30-09:45 Panel discussion: All session faculty 09:35-09:45 Panel discussion: All session faculty
09:45-10:00 Coffee Break
10:00-11:15 COLYM 4: Hodgkin Lymphoma: Optimizing Therapy Across Risk Groups 10:00-11:15 MPNCo&D 4: Transplant, disease evolution, and overlap biology
Moderators: TBA Moderators: Anna Godfrey, UK; Juan Carlos Hernandes-Boluda, Spain
10:00-10:05 Case report: TBA 10:00-10:15 Who should be referred for transplant today — and who is being missed?
TBA
10:05-10:15 Discussion
10:15-10:30 Frontline therapy in advanced-stage classical Hodgkin lymphoma: balancing efficacy and toxicity:
TBA
10:15-10:30 Timing allo-HSCT for atypical MPN: earlier, later, or never?
Nicola Polverelli, Italy
10:30-10:45 PET-adapted and response-adapted strategies: how low can we go?
TBA
10:30-10:45 Overlap syndromes (SM-AHN, MPN with eosinophilia): single disease biology or parallel processes?
Andreas Reiter, Germany
10:45-11:00 Managing relapsed/refractory Hodgkin lymphoma: Checkpoint inhibitors, and beyond:
Graham Collins, UK
10:45-11:00 Lessons learned from two decades of experience with KIT inhibitors in systemic mastocytosis:
Jason Gotlib, USA
11:00-11:15 Panel discussion: All session faculty 11:00-11:15 Advanced systemic mastocytosis treatment in 2026: lessons for risk-adapted therapy in MPNs:
Deepti Radia, UK
11:15-12:30 Industry Symposium 11:15-12:30 Industry Symposium
12:30-13:00 Lunch Break
13:00-14:15 COLYM 5: Rare, Neglected, and Difficult Lymphomas 13:00-14:15 MPNCo&D 5: New options for Essential Thrombocythemia and Polycythemia Vera — are they needed and when should we use them?
Moderators: Mohamed Kharfan-Dabaja, USA; TBA Moderators: Lina Benajiba, France; Claire Woodley, UK
13:00-13:05 Case report: TBA 13:00-13:15 Interferon — which patients with ET and PV should have it and what is the treatment target?
Lina Benajiba, France
13:05-13:15 Discussion
13:15-13:30 Peripheral T-cell lymphomas: are we finally improving outcomes?
Eva Domingo-Domènech, Spain
13:15-13:30 Hepcidin mimetics — how will they be used for PV patients?
Naveen Pemmaraju, USA
13:30-13:45 Primary CNS and extranodal lymphomas: unmet needs and new strategies:
Kate Cwynarski, UK
13:30-13:45 Emerging precision therapies in ET:
Anna Godfrey, UK
13:45-14:00 Management of post-transplant lymphoproliferative disorders (PTLD) and immunodeficiency-associated lymphomas:
TBA
13:45-14:00 MPN Symptom Burden / Navigating ET and PV from Patient and Caregiver Perspective: Clinical Pearls from the Frontlines:
Claire Woodley, UK
14:00-14:15 Panel discussion: All session faculty 14:00-14:15 Panel discussion: All session faculty
14:15-15:30 IACH 4
15:30-15:45 Coffee Break
15:45-16:15 IACH 5
Thursday, October 15th
Hall A Hall B
08:45–09:00
Welcome Coffee
09:00–12:00
IACH 1: Workshop
12:00–12:30
Lunch Break
12:30–13:00
IACH 2: Awards Session
13:00–14:15
Transplant 1
13:00–14:15
COMydAL 1: MDS I
Moderators: TBA
13:00–13:15A new MDS classification ahead? TBA
13:15–13:30AI in diagnosis and prognostication of MDS and CMML: TBA
13:30–13:45Is there a border between AA and hMDS? TBA
13:45–14:00Germline predisposition in MDS, diagnosis and impact on therapy: TBA
14:00–14:15Panel discussion: All session faculty
14:15–15:30
Transplant 2
14:15–15:30
COMydAL 2: MDS II
Moderators: Valeria Santini (Italy); TBA
14:15–14:30Transplant for MDS in 2026? TBA
14:30–14:45Diagnosis and treatment of VEXAS and MDS: TBA
14:45–15:00Therapy of HR MDS: are target drugs the only hope? TBA
15:00–15:15Navigating the treatment of LR-MDS: TBA
15:15–15:30Panel discussion: All session faculty
15:30–16:45
Industry Symposium
15:30–16:45
Industry Symposium
16:45–17:00
Coffee Break
17:00–18:15
Transplant 3
17:00–18:15
COMydAL 3: CMML, MDS/MPN and others
Moderators: Valeria Santini (Italy); TBA
17:00–17:15New directions in management of TP53 mutated myeloid neoplasms: Maximilian Stahl (USA)
17:15–17:30Evolving use of oral HMAs in myeloid malignancies: Daniel Wiseman (UK)
17:30–17:45Recommendation transplantation in CMML and MDS/MPN: TBA
17:45–18:00Biology and treatment of CMML: TBA
18:00–18:15Panel discussion: All session faculty
Friday, October 16th
Hall A Hall B
08:30–09:45
Transplant 4
08:30–09:45
COMydAL 4: AML I
Moderators: Tamara Vasilj (Croatia); Amer Zeidan (USA)
MyeloMatch and pivotal AML studies to watch for in the next 3 years: TBA
An update on FLT3 inhibitors use in AML: TBA
An update on IDH inhibitors use in AML: Stéphane De Botton (France)
An update on menin inhibitors use in AML: Amer Zeidan (USA)
Panel discussion: All session faculty
09:45–10:00
Coffee Break
10:00–11:15
Transplant 5
10:00–11:15
COMydAL 5: AML II
Moderators: Sanam Loghavi (USA); Amer Zeidan (USA)
How should TP53 mutated myeloid neoplasms be classified? TBA
Updates on clinical use of MRD for clinical management of AML: Christoph Röllig (Germany)
Learnings from HARMONY about genetics determinants of outcomes in AML: TBA
Harmonization efforts of classifications for AML and MDS: Sanam Loghavi (USA)
Panel discussion: All session faculty
11:15–12:30
Industry Symposium
11:15–12:30
Industry Symposium
12:30–13:00
Lunch Break
13:00–14:15
COLYM 1: From Biology to Bedside: What Will Really Change Practice?
Moderators: TBA
13:00–13:05
Opening: Claire Harrison (UK); Ruben Mesa (USA); Naveen Pemmaraju (USA)
13:05–14:15
MPNCo&D 1: Redefining disease and risk: are we stratifying patients correctly?
Moderators: Florian Heidel (Germany); TBA
13:00–13:05
Case report: TBA
13:05–13:20
Patient perspective on MPN priorities for 2026 and beyond: Werner Zinkland (Germany)
13:05–13:15
Discussion
13:20–13:35
Molecular risk models vs clinical judgement: are mutations driving overtreatment? Should we use them more in ET and PV: Jean-Jacques Kiladjian (France)
13:15–13:30
Molecular subtyping and functional genomics: what is ready for routine care? TBA
13:35–13:50
Clonal hematopoiesis vs early MPN: when does ‘watch and wait’ become unsafe? TBA
13:30–13:45
ctDNA as a decision-making tool: hype, hope, or hard evidence? Sven Borchmann (Germany)
13:50–14:05
Symptoms, spleen, survival: which outcome should drive first-line therapy choices in MF? Claire Harrison (UK)
13:45–14:00
Emerging biomarkers for response prediction to novel agents: Brian Hill (USA)
14:05–14:15
Panel discussion: All session faculty
14:00–14:15
Panel discussion: All session faculty
14:15–15:30
Industry Symposium
14:15–15:30
Industry Symposium
15:30–16:45
COLYM 2: Redefining Frontline Therapy: Risk, Response, and Reality
Moderators: TBA
15:30–16:45
MPNCo&D 2: Anemia in myelofibrosis: mechanism-driven therapy or trial-and-error?
Moderators: David Ross (Australia); TBA
15:30–15:35
Case report: TBA
15:30–15:45
What causes anemia in MF — cytokines, hepcidin, marrow failure, or treatment effect? David Ross (Australia)
15:35–15:45
Discussion
15:45–16:00
ESAs, danazol, steroids: obsolete, underused, or still foundational? Susanne Isfort (Germany)
15:45–16:00
Biology-driven frontline strategies in aggressive B-cell lymphomas: Andrew Davies (UK)
16:00–16:15
Novel agents targeting anemia pathways in MF: Searching for the Holy Grail: Ruben Mesa (USA)
16:00–16:15
Frontline therapy in high-risk subgroups: elderly fit patients with LBCL: Farrukh Awan (USA)
16:15–16:35
Anemia as a prognostic marker vs a treatment-limiting toxicity: should it dictate therapy choice? Yes: Juan Carlos Hernandes-Boluda (Spain) No: TBA
16:15–16:30
Managing primary refractory and early relapsed aggressive B-cell lymphomas: optimizing salvage and bridging strategies: TBA
16:35–16:45
Panel discussion: All session faculty
16:30–16:45
Panel discussion: All session faculty
16:45–17:00
Coffee Break
17:00–18:15
IACH 3
Saturday, October 17th
Hall A Hall B
08:30–09:45 COLYM 3: Sequencing in Relapsed Lymphoma: Making Sense of Too Many Options Moderators: TBA 08:30–09:45 MPNCo&D 3: Next-generation targeted therapies: beyond JAK inhibition in MF Moderators: Susanne Isfort (Germany); Andreas Reiter (Germany)
08:30–08:35 Case report: TBA 08:30–08:45 Selective pathway targeting (e.g. hepcidin, ACVR1, BCL-2 family, Xpo1, MDM2): real differentiation or incremental gains? Jennifer O’Sullivan (UK)
08:35–08:45 Discussion
08:45–09:00 Bispecific antibodies vs cellular therapies in FL: how to choose in real-life practice: TBA 08:45–09:00 Early signals from novel agents targeting CALR in MF: how should clinicians interpret phase 1-2 data? Bethan Psaila (UK)
09:00–09:15 Treatment sequencing in relapsed / refractory MZL: what do we do next? TBA 09:00–09:15 Early data on novel JAK inhibitors: molecular markers, phenotype, or treatment history? John Mascarenhas (USA)
09:15–09:30 Treatment sequencing in relapsed / refractory MCL: what do we do next? Carlo Visco (Italy) 09:15–09:35 Combination strategies for upfront management: all patients INT-1 or above with splenomegaly and symptoms should receive combination therapy if trials are positive Yes: Francesco Passamonti (Italy) No: Florian Heidel (Germany)
09:30–09:45 Panel discussion: All session faculty 09:35–09:45 Panel discussion: All session faculty
09:45–10:00 Coffee Break
10:00–11:15 COLYM 4: Hodgkin Lymphoma: Optimizing Therapy Across Risk Groups Moderators: TBA 10:00–11:15 MPNCo&D 4: Transplant, disease evolution, and overlap biology Moderators: Anna Godfrey (UK); Juan Carlos Hernandes-Boluda (Spain)
10:00–10:05 Case report: TBA 10:00–10:15 Who should be referred for transplant today — and who is being missed? TBA
10:05–10:15 Discussion
10:15–10:30 Frontline therapy in advanced-stage classical Hodgkin lymphoma: balancing efficacy and toxicity: TBA 10:15–10:30 Timing allo-HSCT for atypical MPN: earlier, later, or never? Nicola Polverelli (Italy)
10:30–10:45 PET-adapted and response-adapted strategies: how low can we go? TBA 10:30–10:45 Overlap syndromes (SM-AHN, MPN with eosinophilia): single disease biology or parallel processes? Andreas Reiter (Germany)
10:45–11:00 Managing relapsed / refractory Hodgkin lymphoma: Checkpoint inhibitors, and beyond: Graham Collins (UK) 10:45–11:00 Lessons learned from two decades of experience with KIT inhibitors in systemic mastocytosis: Jason Gotlib (USA)
11:00–11:15 Panel discussion: All session faculty 11:00–11:15 Advanced systemic mastocytosis treatment in 2026: lessons for risk-adapted therapy in MPNs: Deepti Radia (UK)
11:15–12:30 Industry Symposium 11:15–12:30 Industry Symposium
12:30–13:00 Lunch Break
13:00–14:15 COLYM 5: Rare, Neglected, and Difficult Lymphomas Moderators: TBA 13:00–14:15 MPNCo&D 5: New options for ET and PV — are they needed and when should we use them? Moderators: Claire Woodley (UK); TBA
13:00–13:05 Case report: TBA 13:00–13:15 Interferon — which patients with ET and PV should have it and what is the treatment target? Lina Benajiba (France)
13:05–13:15 Discussion
13:15–13:30 Peripheral T-cell lymphomas: are we finally improving outcomes? Eva Domingo-Domènech (Spain) 13:15–13:30 Hepcidin mimetics — how will they be used for PV patients? Naveen Pemmaraju (USA)
13:30–13:45 Primary CNS and extranodal lymphomas: unmet needs and new strategies: TBA 13:30–13:45 Emerging precision therapies in ET: Anna Godfrey (UK)
13:45–14:00 Management of PTLD and immuno deficiency-associated lymphomas: TBA 13:45–14:00 MPN Symptom Burden / Navigating ET and PV from Patient and Caregiver Perspective: Clinical Pearls from the Frontlines: Claire Woodley (UK)
14:00–14:15 Panel discussion: All session faculty 14:00–14:15 Panel discussion: All session faculty
14:15–15:30 IACH 4
15:30–15:45 Coffee Break
15:45–16:15 IACH 5