Thursday, October 9th
Hall A Hall B
08:45-09:00 Welcome Coffee
09:00-12:00 IACH 1: Transplant Workshop
Moderators: TBA
09:00-09:30 Tailoring the intensity of conditioning: TBA
09:30-10:00 Long-term complications of allo-HSCT: TBA
10:00-10:30 VOD after HSCT: 15 years of progress: TBA
10:30-10:45 Short break
10:45-11:15 Chronic GVHD: from steroids to Rock inhibitors: TBA
11:15-12:00 Real-life clinical cases discussion:
All workshop faculty
11:30-12:00 Industry-supported MTE Session
12:00-12:55 Lunch Break
12:55-14:25 Transplant 1: HLA and Donor Selection 12:55-14:25 MPNCo&D 1: Essential Thrombocytosis in 2025: Updates and New Directions
Moderators: TBA Moderators: Claire Harrison, UK; Naveen Pemmaraju, USA; Ruben Mesa, USA
12:55-13:15 Graft composition of PBSC: TBA 12:55-13:05 Opening Remarks by the MPNCo&D co-Chairs
13:15-13:35 CB expansion: TBA 13:05-13:20 Management of patients with ET in 2025 – state-of-the-art for standard of care:
Anna Godfrey, UK
13:25-13:55 HLA: TBA 13:20-13:35 Future directions and clinical trial approaches in ET:
Claire Harrison, UK
13:55-14:15 Algorithm for donor selection: TBA 13:35-13:50 CALR – Role in pathogenesis and treatment target?
Shannon Elf, USA
14:15-14:25 Panel discussion: All session faculty 13:50-14:05 AI and spatial modeling in MPNs: current and future directions:
Daniel Royston, UK
14:05-14:25 Panel discussion: All session faculty
14:25-14:35 Technical Break
14:35-16:05 Transplant 2: Management of relapse of AML and ALL after alloHCT 14:35-16:05 MPNCo&D 2: Pre-Fibrotic MF and Myelofibrosis
Moderators: TBA Moderators: Ruben Mesa, USA; Francesco Passamonti, Italy
14:35-14:55 Biology of leukemia relapse: TBA 14:35-14:50 A review of pre-fibrotic MF: updates in 2025:
Florian Heidel, Germany
14:55-15:15 Treatment of relapse: TBA 14:50-15:05 State-of-the-art treatment of MF – standard of care options: focus on available JAK inhibitors:
Ruben Mesa, USA
15:15-15:35 Application of DLI: TBA 15:05-15:20 Anemia in MF – management and treatment options: current and future:
Francesco Passamonti, Italy
15:35-15:55 Relapse after CAR-T in ALL: TBA 15:20-15:35 Novel therapies and future clinicial approaches for MF:
John Mascarenhas, USA
15:55-16:05 Panel discussion: All session faculty 15:35-16:05 Panel discussion: All session faculty
16:05-16:15 Coffee Break
16:15-17:45 COLYM 1: General Session 16:15-17:45 MPNCo&D 3: Polcythemia Vera and CHIP/Inflammation in MPNs
Moderators: Stefano Luminari, Italy; Anna Sureda, Spain Moderators: Mary Frances McMullin, UK; Adam Mead, UK
16:15-16:20 Case report 16:15-16:30 PV in 2025: state-of-the-art and standard of care:
Adam Mead, UK
16:20-16:30 Discussion
16:30-16:50 Contribution of genomic to the diagnosis of lymphomas:
Björn Chapuy, Germany
16:30-16:45 Novel therapies in PV – clinical trials:
Susanne Isfort, Germany
16:50-17:10 Innovation in the prognostic assessment of lymphoma patients:
Naren Epperla, USA
16:45-17:00 Reflections on molecular discoveries in enythrocytosis:
Mary Frances McMullin, UK
17:10-17:30 Infections and lymphomas: lessions for the clinicians:
Luca Arcaini, Italy
17:00-17:15 Inflammation states in MPN – lessons from MDS:
Shahram Kordasti, UK
17:30-17:45 Panel discussion: All session faculty 17:15-17:45 Panel discussion: All session faculty
17:45-19:15 COLYM 2: Indolent Lymphomas 17:45-19:15 IACH 2: Progress in the management of GVHD
Moderators: Stefano Luminari, Italy; Jessica Okosun, UK Moderators: TBA
17:45-17:50 Case report 17:45-18:15 Update on the biology of chronic GVHD: TBA
17:50-18:00 Discussion 18:15-19:00 Real-life clinical cases discussion:
All session faculty
18:00-18:20 Transformation in indolent lymphomas: identification, prediction and management:
Jessica Okosun, UK
18:20-18:40 Follicular lymphomas: impact of novel therapies on the treatment algorithm:
Julio Chavez, USA
18:40-19:00 Marginal zone lymphomas: current and future approaches to advanced-stage patients:
Côme Bommier, France
19:00-19:15 Panel discussion: All session faculty
Friday, October 10th
Hall A Hall B
08:00-08:15 Welcome Coffee
08:15-09:45 Transplant 3: ALL Management 08:15-09:45 MPNCo&D 4: Immunotherapy, SCT, Novel Approaches in MPNs
Moderators: TBA Moderators: Anna Godfrey, UK; Susanne Isfort, Germany
08:15-08:35 AlloHCT in ALL: TBA 08:15-08:30 Novel clinical approaches targeting CALR – translational/clinical approaches:
Bethan Psaila, UK
08:35-08:55 Maintenance in ALL after alloHCT: 08:30-09:00 Should blastic phase MPN be aggressively treated?
Yes: Tania Jain, USA
No: Bart Scott, USA
08:55-09:15 CAR-T cell in T-ALL: TBA 09:00-09:15 Recent data to achieve the best from allografting in MF:
Donal McLornan, UK
09:15-09:35 CAR-T in B-ALL ped and adults: TBA 09:15-09:45 Panel discussion: All session faculty
09:35-09:45 Panel discussion: All session facultyaaa
09:45-10:00 Coffee Break
10:00-11:30 Industry-supported Morning Symposium 10:00-11:30 CME Morning Symposium
11:30-11:40 Technical Break
11:40-13:10 Transplant 4: AML Management 11:40-13:10 MPNCo&D 5: Spotlight on Rare MPNs: Not as Rare As You Think
Moderators: TBA Moderators: Deepti Radia, UK; Andreas Reiter, Germany
11:40-12:00 Predictive score for AML: TBA 11:40-11:55 CMML – updates and future directions:
Daniel Wiseman, UK
12:00-12:20 Conditioning regimen in AML: TBA 11:55-12:10 Hypereosinophilic syndromes in 2025:
Andreas Reiter, Germany
12:20-12:40 Maintenance in AML: TBA 12:10-12:25 Systemic mastocytosis:
Deepti Radia, UK
12:40-13:00 CAR-T construct for AML: TBA 12:25-12:40 Focus on rare hematologic malignancies: pearls and reflections:
Naveen Pemmaraju, USA
13:00-13:10 Panel discussion: All session faculty 12:40-13:10 Panel discussion: All session faculty
13:10-13:40 Lunch Break
13:40-15:10 Industry-supported Lunch Symposium 13:40-15:10 Industry-supported Lunch Symposium
15:10-15:20 Technical Break
15:20-16:50 COLYM 3: Chronic Lymphocytic Leukemia 15:20-16:50 COMydAL 1: MDS I
Moderators: Mohamed Kharfan-Dabaja, USA; Stefano Luminari, Italy Moderators: TBA
15:20-15:25 Case report 15:20-15:35 An update on IDH inhibitors in MDS:
Lionel Adès, France
15:25-15:35 Discussion
15:35-15:55 Time-limited vs continuous therapy as front-line treatment of CLL: matching the bset approach to the right patient:
Talha Munir, UK
15:35-15:50 An update on AZA-based combinations in MDS:
Astrid Olsnes, Norway
15:55-16:15 Treatment of relapsed and/or refractory CLL after failure of a covalent BTK and BCL2 inhibitors:
Farrukh Awan, USA
15:50-16:05 An update on immune biomarkers and targeting in MDS:
Shahram Kordasti, UK
16:15-16:35 BTK degraders: what are they and how will they shape CLL management? TBA 16:05-16:20 An update on response and MRD assessment in MDS:
Arjan van Loosdrecht, Netherlands
16:35-16:50 Panel discussion: All session faculty 16:20-16:50 Panel discussion: All session faculty
16:50-17:00 Coffee Break
17:00-18:30 COLYM 4: Hodgkin Lymphoma 17:00-18:30 COMydAL 2: AML I
Moderators: Andrew Evens, USA; Anna Sureda, Spain Moderators: TBA
17:00-17:05 Case report 17:00-17:15 Should FLT3 inhibitors be a frontline therapy for older FLT3-mut AML: TBA
17:05-17:15 Discussion
17:15-17:35 Divide across the pond: how to select between N-AVD or BrECADD in newly diagnosed cHL?
Justin Ferdinandus, Germany
17:15-17:30 AZA-VEN vs AZA-IVO for frontline therapy of older IDH1 mutated AML?
Ume Borate, USA
17:35-17:55 Harnessing predictive modelling for individualized therapy in Hodgkin Lymphoma:
Andrew Evens, USA
17:30-17:45 How should we stratify AML in 2025:
Thomas Cluzeau, France
17:55-18:15 Do all relapsed cHL need an autologous treatment as consolidation?
Christine Mauz-Körholz, Germany
17:45-18:00 An update on menin inhibitors in AML patients:
Amer Zeidan, USA
18:15-18:30 Panel discussion: All session faculty 18:00-18:30 Panel discussion: All session faculty
18:30-19:00 IACH 3: Awards
Saturday, October 11th
Hall A Hall B
08:00-08:15 Welcome Coffee
08:15-09:45 Transplant 5: GVHD 08:15-09:45 IACH 4: Updates in the management of multiple myeloma
Moderators: TBA Moderators: TBA
08:15-08:35 Biomarkers of GVHD for an individualized prophylaxis: TBA 08:15-08:45 Transplant of eligible patients: TBA
08:35-08:55 PTCy tolerance and long-term effect: TBA 08:45-09:15 Non-transplant eligible patients: TBA
08:55-09:15 New treatment for aGVHD: TBA 09:15-09:45 Management of relapse: TBA
09:15-09:35 Management of cGVHD: TBA
09:35-09:45 Panel discussion: All session faculty
09:45-10:00 Coffee Break
10:00-11:00 Industry-supported Symposium 10:00-11:00 Industry-supported Symposium
11:00-11:10 Technical Break
11:10-12:40 COLYM 5: Aggressive B-Cell Lymphoma 11:10-12:40 COMydAL 3: MDS/MPN
Moderators: Anna Sureda, Spain; Mohamed Kharfan-Dabaja, USA Moderators: Lisa Pleyer, Austria & TBA
11:10-11:15 Case report 11:10-11:25 Defining MDS/MPN entities for clinical decision making:
Daniel Wiseman, UK
11:15-11:25 Discussion
11:25-11:45 “All comers” vs “molecularly driven” treatment strategies in first-line DLBCL patients: where are we heading to?
Umberto Vitolo, Italy
11:25-11:40 Molecular classification along the myeloid neoplasm spectrum:
Matteo Della Porta, Italy
11:45-12:05 Changing the field in RR DLBCL: CAR-T cells and BiEsp MoAb: TBA 11:40-11:55 CMML molecular landscape:
Laura Palomo, Spain
12:05-12:25 Is there life after CAR-T? Mechanisms of resistance and potential therapeutic strategies:
Roni Shouval, USA
11:55-12:10 MDS/MPN – an update on therapeutics:
Francesco Onida, Italy
12:25-12:40 Panel discussion: All session faculty 12:10-12:40 Panel discussion: All session faculty
12:40-13:10 Lunch Break
13:10-14:40 COLYM 6: Mantle Cell Lymphoma 13:10-14:40 COMydAL 4: MDS II
Moderators: Marco Ladetto, Italy; Anna Sureda, Spain; TBA Moderators: Sophie Park, France & TBA
13:10-13:15 Case report 13:10-13:25 Dissecting biology of MDS Del5q:
Julia Montoro, Spain
13:15-13:25 Discussion
13:25-13:45 Should we abandon auto-HCT as first-line consolidation therapy in de novo MCL patients?
Olivier Hermine, France
13:25-13:40 Should we improve selection of patients for ESA therapy?
Marco Raddi, Italy
13:45-14:05 Choosing between a BTK inhibitor and CAR-T cell therapy in RR MCL:
Marco Ladetto, Italy
13:40-13:55 Autoimmunity in MDS:
Lin Pierre Zhao, France
14:05-14:25 Management of relapsed TP53 mutated mantle cell lymphoma: is allogeneic HCT still a major player?
Nora Liebers, Germany
13:55-14:10 Evolving therapeutic algorithm for LR MDS: ESA, luspatercept, imetelstat:
Valeria Santini, Italy
14:25-14:40 Panel discussion: All session faculty 14:10-14:40 Panel discussion: All session faculty
14:40-16:00 IACH 5: Advances in CAR-T cells 14:40-16:00 COMydAL 5: AML II
Moderators: TBA Moderators: TBA
14:40-15:10 Plenary lecture: Next generation CAR-T cells: TBA 14:40-14:55 Are retinoids out of fasion in non-APL AML/HR-MDS?
Amy deZern, USA
15:10-15:35 TBA 14:55-15:10 An update on TP53 AML biology and targeting in AML/HR-MDS:
Max Stahl, Germany
15:35-16:00 TBA 15:10-15:25 Germline predisposition in AML and MDS:
Marie Sebert, France
15:25-15:40 The role of inflammation in AML and MDS:
Antonio Curti, Italy
15:40-16:00 Panel discussion: All session faculty
16:00-16:15 Closing Remarks